Golden Rice: A Case Study in Intellectual Property Management and International Capacity Building

The authors examine the management of risks associated with intellectual property linked to agri-biotech products, with emphasis on the international movement of agri-biotech intellectual property from industrialized to developing nations

Golden Rice: A Case Study in Intellectual Property Management and International Capacity Building

In order for agricultural biotechnology (agri-biotech) to play a larger role in the development of sustainable agricultural systems, intellectual property (IP) rights management must be addressed. These issues are not limited to developing countries. With increased globalization, the management of agri-biotech IP rights affects both developing and industrialized countries. In industrialized countries, for example, IP rights risk management entails protection of inventions via strong patent portfolios. For developing countries, IP rights risk management includes the acquisition of rights requisite for the use of inventions essential to the basic welfare of the population. Strategies are needed to bridge these disparate IP management paradigms to facilitate the successful transfer of the agri-biotech from an industrialized country source to a developing country recipient. This paper examines IP management linked to agri-biotech products. Further, this paper examines Golden Rice, a genetically engineered rice strain that accumulates beta-carotene (i.e., pro-vitamin A) in the endosperm tissue of grain, as a case study for IP management, with emphasis on the international movement of agri-biotech from industrialized to developing countries. Topics discussed include: the application of agri-biotech to international development; the challenge of transferring this technology from industrialized to developing countries; a method for evaluating the IP constraints impinging on the deployment of Golden Rice; industrialized/developing country perspectives vis-a-vis IP rights management; six shorter-term options for the management of IP connected to Golden Rice; and a longer-term proposed path to sustainable transfers of agri-biotech products

Elliptic curves with a given number of points over finite fields

Given an elliptic curve $E$ and a positive integer $N$, we consider the problem of counting the number of primes $p$ for which the reduction of $E$ modulo $p$ possesses exactly $N$ points over $\mathbb F_p$. On average (over a family of elliptic curves), we show bounds that are significantly better than what is trivially obtained by the Hasse bound. Under some additional hypotheses, including a conjecture concerning the short interval distribution of primes in arithmetic progressions, we obtain an asymptotic formula for the average.Comment: A mistake was discovered in the derivation of the product formula for K(N). The included corrigendum corrects this mistake. All page numbers in the corrigendum refer to the journal version of the manuscrip

Three-dimensional laser window formation for industrial application

The NASA Lewis Research Center has developed and implemented a unique process for forming flawless three-dimensional, compound-curvature laser windows to extreme accuracies. These windows represent an integral component of specialized nonintrusive laser data acquisition systems that are used in a variety of compressor and turbine research testing facilities. These windows are molded to the flow surface profile of turbine and compressor casings and are required to withstand extremely high pressures and temperatures. This method of glass formation could also be used to form compound-curvature mirrors that would require little polishing and for a variety of industrial applications, including research view ports for testing devices and view ports for factory machines with compound-curvature casings. Currently, sodium-alumino-silicate glass is recommended for three-dimensional laser windows because of its high strength due to chemical strengthening and its optical clarity. This paper discusses the main aspects of three-dimensional laser window formation. It focuses on the unique methodology and the peculiarities that are associated with the formation of these windows

The Intellectual and Technical Property Components of pro-Vitamin A Rice (GoldenRiceTM): A Preliminary Freedom-To-Operate Review

Rice is a staple food for millions of people, predominantly in Asia, but lacks essential nutritional components such as Vitamin A. This is very important for over 180 million children and women of child bearing age who suffer from Vitamin A deficiency in Asia alone. For this reason, an improvement was made under an effort led by Profs. Ingo Potrykus and Peter Beyer by inserting several genes into rice to produce an improved product called GoldenRice. Because GoldenRice has the potential to be easily integrated into the farming systems of the world\u27s poorer regions, the advent of GoldenRice promises to go a long way towards solving Asia\u27s Vitamin A deficiency problem in an effective, inexpensive, and sustainable way. As a result of the increasing complexity of the intellectual property (IP) framework under which the international agricultural development community operates, the Rockefeller Foundation funded an ISAAA project to conduct a selective Freedom-To-Operate (FTO) analysis of GoldenRice with the objectives of reviewing the IP and Technical Property (TP; or tangible property) components associated with GoldenRice; providing institutions interested in distributing GoldenRice with the information needed to develop strategic options for handling the proprietary science embedded in the product; and developing possible alternative strategies on how the IP/TP constraints could be managed effectively. Any FTO opinion is a risk management opinion and its results vary on a country-by-country basis. It is a dynamic opinion; never a definitive answer. Hence the present document serves as an analytical framework that can serve as the basis of a legal FTO review

Causal sets and conservation laws in tests of Lorentz symmetry

Many of the most important astrophysical tests of Lorentz symmetry also assume that energy-momentum of the observed particles is exactly conserved. In the causal set approach to quantum gravity a particular kind of Lorentz symmetry holds but energy-momentum conservation may be violated. We show that incorrectly assuming exact conservation can give rise to a spurious signal of Lorentz symmetry violation for a causal set. However, the size of this spurious signal is much smaller than can be currently detected and hence astrophysical Lorentz symmetry tests as currently performed are safe from causal set induced violations of energy-momentum conservation.Comment: 8 pages, matches version published in PR

In and Out of Place: Islamic Domestic Extremism and the Case of the "Toronto 18"

In the aftermath of the tragic events of 11 September 2001 a veritable cornucopia of formal, practical, and popular materials have emerged that offer analyses of various dimensions of the phenomenon of Islamitic extremism. Unfortunately, despite the voluminous amount of analytical capital and resources expended, significant advances in our collective understanding of this phenomenon continue to be elusive. This situation is certainly evident when one surveys the current literature available that focuses on the processes of Islamitic extremization. To date, the predominant focus of this important research has been on the micro social relations and structures that make the development of particular subjectivities probable. Although this mode of inquiry is valuable, there is a danger in overly subjectivizing the process of extremization. As demonstrated through an analysis of the so-called Toronto 18—a group of Islamitic social actors apprehended in June, 2006, for activities that contravened the Canadian Anti-Terrorism Act (ATA)—macro social relations and structures served a significant function in creating the conditions through which the process of extremization becomes probable. In the context of this analysis, the macro social relations and structures that made the ideological conditioning and political transformation of these Islamitic social actors probable include, what is referred to as, the following spheres of influence: Transnational, State, and Group. In effect, these spheres of influence formed a network of scales that converged and condensed in the place-specific context of the Greater Toronto Area (GTA) and facilitated the transgression of some of the actors involved from a Dominant to a Subversive discursive formation and concomitant field of action and practice. However, to develop a greater appreciation for the context within which these processes took place required not only a re-evaluation of the conceptual and terminological tools used to apprehend this phenomenon, but an analysis of the historical processes and forces that made the emergence of particular discursive formations possible. If a comprehensive understanding of the processes of extremization are to be reached and effective counter- terrorism policies developed, the macro social relations and structures that make the emergence of particular extremist subjectivities probable need to be given greater consideration. Ignoring these relations and structures will potentially result in the continuation of counter-productive anti-terrorism policies and counter-terrorism practices which contribute to the oxygen of violence rather than facilitating the de-escalation of extremist activities